Background: Pilomatrixoma is a benign tumor with differentiation toward hair cells. It is a rare, benign, slow-growing skin tumor firstly described by Malhebre and Chenantais in 1880. It usually occurs as a solitary lesion mostly located in the head and neck as a firm, deep-seated nodule covered by normal skin.
Case: Our study evaluate retrospectively the clinical and cytomorphologic features of seven cases of pilomatrixoma.
In the smears stained with MGG malignancy was excluded. The diagnosis of pilomatrixoma was confirmed by pathologist. A semiquantitative method was used in evaluation of the following features: basaloid cells, shadow cells, inflammatory cells, giant cells, naked nuclei, and debris (0 absent, 1+ mild amount, 2+ moderate, 3+ abundant).
The maximum score obtained in FNA was for basaloid cells 13/21, shadow cells 14/21 and giant cells 11/21 while in the histological sections, the maximum score for basaloid cells was 20/21 and for shadow cells 17/21.
Conclusion: The presence of basaloid cells, ghost cells and giant cells in cytological smears and also clinical information as a localization in the head and neck region, then a slowly growing tumor of the skin or subcutaneous tissue will allow a conclusive diagnosis of pilomatrixoma by FNA.Pilomatriksom je benigni tumor porijekla stanica dlačnog folikula. On je rijetki, benigni, sporo rastući kožni tumor kojeg su prvi puta opisali Malhebre i Chenantais 1880. godine. Pojavljuje se obično kao pojedinačna lezija, najčešće na glavi i vratu kao tvrdi, dublje smješten čvor prekriven normalnom kožom.
Naša studija retrospektivno evaluira kliničke i citomorfološke značajke sedam slučajeva pilomatriksoma.
U razmazima koji su bili bojeni MGGom isključen je malignitet. Dijagnoza pilomatriksoma potvrđena je histološki. Upotrebljena je semikvantitativna metoda u analizi sljedećih karakteristika: bazaloidne stanice, anuklerane stanice, upalne stanice, divovske stanice, gole jezgre, i detritus (O negativno, 1+ mala zastupljenost, 2+ srednja zastupljenost, 3+ obilno).
Maksimalan rezultat dobiven aspiracijskom citodijagnostikom iznosio je za bazaloidne stanice 13/21, anuklearne stanice 14/21 i divovske stanice 11/21, dok su histološkom analizom dobiveni rezultati za bazaloidne stanice 20/21 i za anuklearne stanice 17/21.
Prisutnost bazaloidnih stanica, anuklearnih stanica i divovskih stanica u citološkim razmazima kao i kliničke informacije o lokalizaciji u području glave i vrata, te o sporo rastućem tumoru kože i potkožnog tkiva upućivat će u citodijagnostici na zaključnu dijagnozu pilomatriksoma
