New Syntheses of Thiazole and Thiophene Derivatives

Abstract

A novel synthesis of methylenebis(A2-l,3-thiaizoline-4-one) via reaction of chloroacetic acid wiith (A2-l,3-thiazoline-4-one- -2-yl)thioacetamide and a new route for synthesis of 2-aryl-4- -oxothiolane-3,3-dicarbonitrile via the reaction of thioglycolic acid with 3-aryl-2-cyanothioacrylamides are reported. The reaction of aromatic aldehydes and arenediazonium Chloride with active methylene compounds is discussed. The structures of all new compounds are established and the mechanism proposed for some reactions

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