Sestre Milosrdnice University hospital and Institute of Clinical Medical Research
Abstract
The aim of the study was to assess the characteristics and clinical features of orbital meningiomas during a 5-year period (2001-2005). Due to their typical posterior location, slowly progressive and painless visual loss, orbital meningiomas are intriguing and challenging lesions to diagnose and manage. This prospective study identified five cases (four female, mean age 46.5±14.5 years and one male aged 68 years) of orbital meningiomas, treated at University Department of Ophthalmology, Split University Hospital in Split from January 2001 until December 2005. In each case, the diagnosis was confirmed by history review. In our study, the incidence of orbital meningiomas was 0.2 per 100,000 inhabitants, however, some cases may have been recognized and treated at other hospitals in Croatia. In this study, orbital meningiomas showed a female predominance (F/M, 4:1). The mean visual acuity was 0.7 (range 0.4-0.9). Discrete proptosis was found in two cases with a slightly blurred optic disc margin and discrete optic disc edema. Optic nerve discoloration was observed in three cases. In one case, meningioma showed intracranial extension. Mild optic disc discoloration and blurred optic disc margin with slow and painless visual loss, particularly in females, may be the first signs of orbital meningioma.Meningeomi orbite zbog svoje stražnje lokalizacije i polaganog bezbolnog gubitka vida često predstavljaju dijagnostički i terapijski izazov. Cilj rada bio je ispitati incidenciju meningeoma orbite tijekom 5 godina (siječanj 2001. - prosinac 2005.) na Klinici za očne bolesti Kliničke bolnice Split. Retrospektivnom analizom su ispitane povijesti bolesti petoro bolesnika s kliničkom dijagnozom meningeoma orbita, liječenih na našoj Klinici. Analiza je obuhvatila četiri žene srednje dobi 46,5±14,5 godina i jednog muškarca starog 68 godina. Incidencija meningeoma orbite u našem ispitivanju bila je 0,2 na 100.000 stanovnika, iako je moguće da su neki bolesnici dijagnosticirani i liječeni na drugim klinikama u Hrvatskoj. Meningeomi orbita su bili češći kod žena nego kod muškaraca (4:1). Srednja vidna oštrina je bila 0,7 (raspon 0,4-0,9). Diskretna proptoza s nejasnim granicama i blagim edemom glave vidnog živca nađena je u dva slučaja, a diskoloracija vidnog živca u druga tri slučaja. Kod jednog bolesnika meningeom orbite je očitovao intrakranijsku ekstenziju. Blagi i bezbolni pad oštrine vida jednoga oka, diskoloracija i nejasne granice vidnog živca na očnoj pozadini, naročito kod žena, mogu biti prvi znaci meningeoma orbite
