University Hospital for Tumors, University Hospital Center Sestre milosrdnice
Abstract
Head and neck squamous cell carcinoma is the sixth most common malignancy. High morbidity and mortality, lack of response to radio-and chemotherapy and signifi cant reduction in the quality of life in patients after surgical procedures in the head and neck region stress the need for more eff ective methods of diagnosis, treatment and prevention of disease recurrence. In the past, pathologist only defined the diagnosis, today pathologist also determines the prognostic and predictive
factors that are important in the treatment of patients. This places the pathologist in the core of in a multidisciplinary team for head and neck cancer and decision making.Karcinom pločastih stanica glave i vrata je na šestom mjestu zloćudnih tumora. Karakterizira ga visoka incidencija i visoka smrtnost, također ne pokazuje očekivani odgovor na zračenje i kemoterapiju, a vidljiva je značajno umanjena kvaliteta života u bolesnika nakon kirurškog liječenja. Sve to zahtjeva traženje mnogo učinkovitijih metoda u dijagnosticiu i liječenju kao i prevenciji bolesti. U prošlosti je patolog samo postavio dijagnozu, danas treba odrediti prognostičke i prediktivne
čimbenike koji su važni za liječenje bolesnika. Patolog je postao jedna od ključnih osoba u multidisciplinarnom timu karcinoma glave
