Alessandra Fusco

Giovanna Donnarumma

Michelina Catauro

Monica Gallo

Pina Caputo

English

Archivio Istituzionale della Ricerca - Università degli Studi della Campania "Luigi Vanvitelli"

Polcom 2020 Abstract  Sol-gel synthesis and antibacterial characterization of bioactive ferrous citrate-silica hybrid materials  A. Fusco*1, G. Donnarumma1 , P. Caputo1, M.Gallo2 , M.Catauro3  1Dipartimento di Medicina Sperimentale, Sezione di Microbiologia e Microbiologia clinica, University of Campania “Luigi Vanvitelli”, Via Santa Marai di Costantinopoli, 16 80138 , Naples, Italy. 24Department of Molecular Medicine and Medical Biotechnology, University of Naples Federico II, via Pansini, 5; 80131 Naples, Italy. 3Department of Engineering, University of Campania “Luigi Vanvitelli”, via Roma 29, I-81031 Aversa, Italy.  *corresponding author: alessandra.fusco@unicampania.it  Keywords. -gel; ferrous citrate; FTIR analysis; drug release; antibacterial properties  Abstract.  Imbalance of the iron level in the body causes several diseases. In particular, the low level of iron, during pregnancy, is responsible the iron deficiency anemia, and even of neurodegenerative diseases. Although the treatment of iron deficiency anemia with oral iron supplements has been known, this problem still afflicts many people. The aim of this work was the synthesis of therapeutic systems, iron (II) based, by sol-gel method. In a SiO2 matrix were embedded different weight percentages ferrous citrate (Fe(II)C. Fourier Transform Infrared (FTIR) spectroscopy was used to study the interactions among different components in the hybrid materials. The bioactivity of the synthesized hybrid materials was evaluated by the formation of a layer of hydroxyapatite on the surface of samples soaked in SBF using FTIR spectroscopy. Finally, also, the potential antibacterial properties of the different materials against two different bacteria, Staphylococcus epidermidis and Pseudomonas aeruginosa, were investigated.  

Sol-gel synthesis and antibacterial characterization of bioactive ferrous citrate-silica

https://iris.unicampania.it/bitstream/11591/466416/1/Abstract%20Fusco%20Polcom2020.pdf

Sol-gel synthesis and antibacterial characterization of bioactive ferrous citrate-silica

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Archivio Istituzionale della Ricerca - Università degli Studi della Campania "Luigi Vanvitelli"