Holick, Katie M.

English

University of Montana

University of Montana ScholarWorks at University of Montana University of Montana Course Syllabi Open Educational Resources (OER) Summer 6-1-2022 BIOB 260.01: Cellular and Molecular Biology Katie M. Holick University of Montana, Missoula, katie.holick@umontana.edu Follow this and additional works at: https://scholarworks.umt.edu/syllabi Let us know how access to this document benefits you. Recommended Citation Holick, Katie M., "BIOB 260.01: Cellular and Molecular Biology" (2022). University of Montana Course Syllabi. 12585. https://scholarworks.umt.edu/syllabi/12585 This Syllabus is brought to you for free and open access by the Open Educational Resources (OER) at ScholarWorks at University of Montana. It has been accepted for inclusion in University of Montana Course Syllabi by an authorized administrator of ScholarWorks at University of Montana. For more information, please contact scholarworks@mso.umt.edu.  CELLULAR AND MOLECULAR (BIOB 260) SUMMER 2022   Professor: Dr. Katie Holick  Lectures: M-F 8:00-10:00 am, ISB 110  Email: katie.holick@umt.edu  Office Hours: By appt. Live or ZoomBIOB 260 introduces the basic building blocks and higher order structures required for cellular processes. Students are expected to take a very active role in their learning by completing readings and homework before and after class and coming to class ready to participate directly with peers and through in-class technology. In this highly structured course, there is evidence that every student can achieve if they are motivated to be an active learner!  OFFICE HOURS: Don’t feel intimidated if you’ve never been to a professor’s office hours. You can come alone or with a friend. You can come in to talk about the course, study skills, concerns, your background, your career, advice for future courses to take, etc. Studies have shown that students who make an effort to get to know their professors outside of the classroom setting, such as in office hours or even asking questions after class, are more likely to succeed in college.  REQUIRED MATERIALS:  1. Essential Cell Biology, Alberts, 5th Edition  MOODLE: MOODLE will have postings from our lectures such as powerpoint slides, handouts, answer keys and supplemental material that I mention in lecture. I will also post announcements on this site.   It is your responsibility to check Moodle regularly and receive email announcements. CLASS STRUCTURE: This class will require that you take an active part in the learning process. This may seem that it makes the course more challenging, but it is my goal to make this course more fun and interesting at the same time. In general, your time in class will be spent in a mix of traditional lectures, class discussions, and some activities. COURSE GOALS:  1. This course should prepare you to succeed in future science courses. You should learn how to be an active learner in the lecture hall and you should learn how to actively study. Educational research has shown that students who do reading/homework before class, actively participate in class, and review notes regularly can and will succeed. Feeling underprepared because of your background?  The course is designed to equalize your readiness before class—while you may take several hours reading and preparing, another student may need less time. Yet when you get to class, your effort will pay off as we practice these concepts together and you gain confidence in your ability! How do you know you are learning? When you make mistakes and identify what you don’t know. Making mistakes is KEY to learning. It makes more sense to make mistakes on homework and in-class when the stakes are very low, rather than on an exam, right?   And what if you don’t plan to take any more   science classes? Active learning and studying are   skills needed for any discipline. You can achieve   these goals through practice. Most students enter   college very skilled at remembering and   understanding (regurgitating memorized  information.) To the right you can see the   “Amended Bloom’s Taxonomy” pyramid. It was   developed as a method of classifying educational   goals for student performance evaluation. I am  looking for you to advance over the semester to  applying and analyzing. True learning will take   place, when you are challenged to apply, analyze,   evaluate, and synthesize. I will challenge you to do   this. You might find this difficult and uncomfortable afirst, but you will be learning!  t 2. This course should provide you with the concepts and skills that make up the scientific field of biology. For those of you continuing in biology, this is just the tip of the iceberg. For others, this might be your one and only biology course! Our goal will be to touch upon many topics, finding common themes in the chapters we cover, such as how the theory of evolution applies to chapters not specifically about evolution. Thoroughly learning the principles is about making connections between material learned at the beginning, middle, and end of the semester! Practice is key to building a foundation of knowledge (and that is why you do reading, quizzes, homework, in-class activities, recitation, etc.).  LEARNING OUTCOMES:  • Define and distinguish atoms, molecules, compounds, chemical bonds, mechanisms of chemical bond formation, and name and recognize the components of biological molecules.  • Describe the structure and function of the organelles in a eukaryotic cell.  • Interpret and compare processes of metabolism including cellular respiration and photosynthesis.  • Describe the process of DNA replication, protein synthesis, mutation, and methods used in DNA technology, and predict the outcomes when given a particular nucleotide or amino acid sequence.  • Discuss the events of cell division.  • Critically evaluate current biological problems as they pertain to society and the environment. • Make conclusions from data and draw graphs and models from data/information given to you. 3. This course should excite you about biology. Throughout the semester I hope you will ask yourself and me, why is this relevant to me? Some lessons will be more obvious as they relate to health and medicine. I hope that the biology that we learn this semester will cause you to ask more questions. You might even leave with more questions than answers! I’ll continually encourage you to read about biological issues and advances in the popular media. If I succeed in getting you to read some articles on your own, I will be a happy professor!   Course Policies:   1. NO MAKEUP EXAMS, QUIZZES, OR HOMEWORK WILL BE GIVEN.  2. Exam and assignment Regrades: You have two weeks following an exam return to request a regrade from Dr. Holick. Any request must be justified with a full written explanation. Please note that as your entire exam is reassessed, this has sometimes resulted in a loss of points when other grading errors were discovered. After the two-week period, no other regrades requests will be accepted.   5. Quizzes & Study Guides: Quizzes and Study Guide assignments can be found online on Moodle.  Late quizzes/Study Guides will receive a zero. Study Guides are based on the assigned reading/posted lectures and assume you have done the reading prior to taking the quiz. Study Guides would be preferably done before class and will be due at the end of class (the last 30 mins will be dedicated to this). Quizzes are due by the end of the day on Thursdays. Many assignments will have a review component of previous material too.  You may drop your three lowest Study Guides and three lowest quiz scores.  6. Exams: Five exams and one final exam will be given. Semester exams are given on Fridays during class time.  Your lowest exam grade will be dropped. The final examination is cumulative and must be completed to receive a final grade.  Failure to take the final exam will result in a failing grade. All students are expected to take all exams when they are scheduled. Students are expected to notify the instructor prior to missing an exam. Students are responsible for any changes in dates of scheduled exams, quizzes, or assignments or any other administrative announcement made during lectures.  7. Writing assignment - Your assignment is to write an opinion piece on any issue in cell biology you care about. Your piece must be 500-750 words. You must have at least 5 CREDIBLE citations and one must be from a primary literature source. You must take a stance on the issue. However, do not rant, but present a well-reasoned argument. Be sure to acknowledge to other side of the issue. If you think other side is wrong, you can also base you piece on dismantling it using your references. Offer solutions and/or compromises in your piece. Your piece must be for a general audience: persons with very limited biology knowledge. You should use examples and analogies to explain any biology concepts. Look for great examples that will bring your argument to life, including personal stories/connections.    Your performance will be evaluated as follows:  % # Points/Item Total Points   Final Project  10.5% 1 100 100 Quizzes  14.2% 15 10 150 Study assignments  14.2% 15 10 150 Semester Exams  57.1% 4 150 600 Cumulative Final Exam  4.8% 1 50 50 Total  100%   1050   Final letter grades will be assigned as follows: Points % Grade  Points % Grade 930-1000  93-100  A  730-769  73-76.9  C 900-929  90-92.9  A-  700-729  70-72.9  C  870-899  87-89.9  B+  670-699  67-69.9  D+ 830-869  83-86.9  B  630-669  63-66.9  D 800-829  80-82.9  B-  600-629  60-62.9  D  770-799  77-79.9  C+  <600  <60  F  Disability Modifications: The University of Montana assures equal access to instruction through collaboration between students with disabilities, instructors, and the Office of Disability Equity (ODE, formerly Disability Services for Students). If you think you may have a disability adversely affecting your academic performance, and you have not already registered with ODE, please contact ODE in Lommasson Center 154 or call (406) 243-2243. I will work with you and ODE to provide an appropriate modification.                                     Lecture Schedule This is a tentative schedule. I reserve the right to make changes that I think are in the best interest of all students. Week  Topics/Chapter  Objectives  Date Lecture Due       1   Chapter 1- Cells: The   Fundamental Units of Life Chapter 2- Chemical   Components of Cells Describe the structure of the cell and organelles.  Distinguish among elements, atoms, compounds and the different types of chemical bonds. Monday Tuesday 1 2 SG1 SG2 Chapter 3- Energy,   Catalysis and Biosynthesis Describe how the metabolic reactions in the cell transforms energy, produces ATP, and drives cell function.  Recall chemical reactions and free energy. Wednesday Thursday 3 4  SG3 SG4 Q1, Q2 Q3, Q4  Exam 1 (Chapters 1-3) Friday  Exam 1       2 Chapter 4- Protein Structure and Function Explain how enzymes function.  Describe protein structure, and how this influences function.  Describe how proteins are regulated. Monday Tuesday 5 6  SG5 SG6 Chapter 5- DNA and   Chromosomes  Chapter 6- DNA   Replication, Repair and  Recombination Describe the structure of DNA  Compare DNA packaging in pro- and eukaryotes   Outline the process of DNA replication Describe the different types of DNA repair Wednesday Thursday 7 8 SG7 SG8 Q5, Q6, Q7, Q8 Exam 2 (Chapters 4-6) Friday  Exam 2      3 Chapter 7- From DNA to Protein: How Cells Read the Genome Outline the steps of transcription & translation  Compare transcription & translation in eukaryotes and prokaryotes  Discuss RNA processing  Compare DNA and RNA structure Discuss the “RNA world hypothesis” Monday Tuesday 9 10 SG9 SG10       3 Chapter 11- Membrane Structure Describe the structure and composition of the lipid membrane  Discuss structure of membrane proteins Explain membrane potentials Wednesday Thursday 11 12 SG11 SG12 Q9, Q10, Q11, Q12  Exam 3 (Chapters 7, 11) Friday  Exam 3           4 Chapter 12-Transport   Across Cell Membranes Compare passive and active membrane transport  Describe the function of ion channels Describe an action potential Monday  13  SG13  Chapter 13- How Cells Obtain Energy from Food  Chapter 14- Energy   Generation from   Mitochondria and   Chloroplasts Detail the steps and outcomes glycolysis Detail the steps and outcomes of the citric acid cycle   Describe oxidative phosphorylation and the generation of ATP in mitochondria the electron transport chain.  Detail the photosynthetic process, including the function of the   photosystems. Tuesday Wednesday Thursday 14 15 16 SG14 SG15 SG16  Exam 4 (Chapters 12, 13-14) Friday  Exam 4         5  Chapter 6- Cell Signaling  Chpt. 17- Cytoskeleton  Chpt. 8- The Cell Division Cycle  Chpt. 19- Sexual   Reproduction and the Power of Genetics Describe the different mechanisms of cell signaling pathways.   Describe the three types of cytoskeletal protein filaments.  Describe the cell cycle.  Compare and contrast mitosis & meiosis. Monday Tuesday Wednesday 15 16 17 SG15 SG16 SG17  Chapter 20- Cell   Communities: Tissues Stem Cells and Cancer Describe the properties and functions of stem cells.   Thursday 18  SG18, Q15, Q16, Q17, Q18   FINAL EXAM (Cumulative) Friday Exam You’ve read to the end of the syllabus!!   

BIOB 260.01: Cellular and Molecular Biology

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BIOB 260.01: Cellular and Molecular Biology

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