Malignant Fibrous Histiocytoma Arising in Previous Surgical Sites.Report of Two Cases

Abstract

Two patients who developed malignant fibrous histiocytoma in previous surgical sites are reported. One patient developed malignant fibrous histiocytoma in an amputation site, and the other patient developed it in a previous hernioplasty scar. Both patients presented with a mass, clinically interpreted as a subcutaneous abscess. The light microscopic and fine structural features of these tumors are described. A possible causal relationship between previous surgery and malignant fibrous histiocytoma is discussed in view of other reported cases arising in various conditions following chronic reparative reactions. Cancer 53:176‐183, 1984