Recent advancements in the area of Artificial Intelligence (AI) have made it the field of choice for automatically processing and summarizing information in big-data domains such as high-resolution images. This approach, however, is not a one-size-fits-all solution, and must be tailored to each application. Furthermore, each application comes with its own unique set of challenges including technical variations, validation of AI solutions, and contextual information. These challenges are addressed in three human-health and safety related applications: (i) an early warning system of slope failures in open-pit mining operations; (ii) the modeling and characterization of 3D cell culture models imaged with confocal microscopy; and (iii) precision medicine of biomarker discovery from patients with glioblastoma multiforme through digital pathology. The methodologies and results in each of these domains show how tailor-made AI solutions can be used for automatically extracting and summarizing pertinent information from big-data applications for enhanced decision making
