Efficacy of combined traditional Chinese medicine spray with premature
ejaculation desensitization therapy for the treatment of primary
premature ejaculation.
Objectives: We recommend a new kind of spray made from eight kinds of
traditional Chinese medicine, we aimed to investigate the safety and
clinical efficacy of combined traditional Chinese medicine spray (TCMS)
with premature ejaculation desensitization therapy (PEDT) for the
treatment of primary premature ejaculation (PPE). Methods: A total of
90 patients with PPE were randomly assigned to receive TCMS, PEDT
monotherapy or TCMS plus PEDT combination therapy for 6 weeks.
Intravaginal ejaculation latency time (IELT) and Chinese index of
sexual function for premature ejaculation (CIPE-5) were measured to
evaluate the effect of each treatment. Results: Eighty six (86)
participants completed the study voluntarily. Both IELT and CIPE-5 in
these three groups increased after treatment when compared with
baseline levels (p< 0.01). IELT and CIPE-5 after treatment in TCMS
plus PEDT group were significantly higher than those in the other two
groups (both p <0.05). Additionally, clinical efficacy in TCMS plus
PEDT group (89.7%) was significantly higher than in TCMS (65.5%) and
PEDT group (67.9%) (p< 0.01). Conclusion: The self-made TCMS was
safe and effective for the treatment of PPE, a combination of TCMS and
PEDT therapy was more effective than the TCMS or PEDT monotherapy