Medknow Publications on behalf of Indian Cancer Society
Abstract
Although glandular and stromal proliferations of prostate are very
common in adult men, neoplastic proliferations of prostatic stroma are
distinctly uncommon. These tumors are now grouped as Prostatic Stromal
Proliferations of Uncertain Malignant Potential (PSPUMP). Phyllodes
tumor of the prostate is a rare neoplasm in this group with cellular,
sarcomatoid stroma and benign hyperplastic glands. It is a locally
expansile tumor with clinical course varying from benign to aggressive.
We report a case of a 45-year-old man presented with retention of urine
and abdominal lump. On laparotomy it was a huge tumor of 4 kg and was
histologicaly characterized by cellular pleomorphic stroma and
hyperplastic epithelium. Immunohistochemistry demonstrated prostate
specific antigen in the glands. It was diagnosed as cystosarcoma
phyllodes tumor of prostate. This is extremely uncommon tumor similar
in histology to that of breast and it\u2032s clinical course varies
with the grade. The patient was without recurrence one year after
surgery