In the last decade, several investigators have reported that autologous and homologous fresh frozen (FFB) and cryopreserved homologue bones (CFFB) are effective materials to restore alveolar ridges previous to insert dental implants. Here we reported a histological comparative study on implants inserted in FFB and CFFB to detect the osteogenic potential of the two types of grafts. Patients were treated with a split mouth scheme for sinus lift with FFB and CFFB bone grafting and immediate implant insertion to evaluate the bone implant contact after 6 months. Three patients were enrolled, 2 males and 1 female, median age 52 years. They were treated at the Department of Maxillofacial Surgery, Civil Hospital, Castelfranco Veneto, Italy in the period January 2008 – December 2008. The study was approved by the Local Ethical Commetee. Histological evaluation was performed on bone speciments containing spiral implants (Alpha Bio LTD, Petah-Tikva, Israel) after 6 months. Statistical test demonstrated that no difference exists between dental implants inserted in FFB and CFFB. However, FFB has a higher values of Vital Bone Volume Percentage suggesting it has higher potential in bone regeneration. In conclusion, iliac crest FFB and CFFB are valuable materials for alveolar ridge augmentation and implant insertion. Spiral implants can be immediately inserted in grafted bone
