Achievement in a subject is more meaningful when a learner is able to retain the knowledge gained for a longer period of time. This study therefore focused on the need to enhance college of education students’ retention through video, animation and audio voice thread modes in North-central Nigeria. Three research questions raised were answered and three null hypotheses were also tested at 0.05 level of significance. The study adopted a quazi-experimental design in which intact classes of students in participating schools were used. A multi-stage sampling technique was used and a total of 210 students constituted sample size of the study. Intact classes of students were randomly assigned to experimental group I (voice thread video mode), experimental group II (voice thread animation mode), and the control group (voice thread audio mode). Voice thread modes were used as treatment instrument while computer science achievement test which was administered at posttest and retention test was used for data collection. The instrument was satisfactorily subjected to validation and reliability checks. Data collected were analyzed using mean, standard deviation and Analysis of Covariance statistics. Findings that emanated from the study revealed that the retention ability of both male and female students were enhanced by video and animation voice thread modes better than the audio mode. It was recommended that these two modes should be integrated in teaching and learning in colleges of education for improved retention of students in computer science