Synthesis of Novel Antipyrine Derivatives Possessing Remarkable Antimicrobial Activities

Abstract

WOS: 000498981700012In this study, new triazole, thiazole, oxazole and Mannich bases were synthesized starting from antipyrine. All the newly synthesized compounds were screened for their antimicrobial activities against some test microorganisms and among them most of them show very good antituberculosis activity beside gram positive and gram negative bacteria. the structures of all synthesized compounds were determined by spectroscopic methods such as FT-IR, H-1 NMR and C-13 NMR.Scientific research project of Karadeniz Technical University (KTU-BAP) [5289]This work was supported by the Scientific research project of Karadeniz Technical University (KTU-BAP) [grant numbers 5289]

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