Ahn, Youngkeun

Hong, Young Joon

Jeong, Myung Ho

Kim, Ju Han

Kim, Min Chul

Kim, Yongcheol

Sim, Doo Sun

English

Via Medica Journals

Address for correspondence: Myung Ho Jeong, MD, Cardiovascular Convergence Research Center of Chonnam National University Hospital, Gwangju 501-757, Republic of Korea, tel: 82-62-220-6243, fax: 82-62-228-7174,  e-mail: myungho@chollian.netReceived: 10.09.2017 Accepted: 10.09.2017Very late stent thrombosis derived from thin-cap neoatheroma and fibroatheroma with plaque  rupture assessed by optical coherence tomographyYongcheol Kim, Myung Ho Jeong, Min Chul Kim, Doo Sun Sim,  Young Joon Hong, Ju Han Kim, Youngkeun AhnDivision of Cardiology, Chonnam National University Hospital, Gwangju, KoreaA 49-year-old woman presented with sudden onset chest pain, at rest, evident of ST-segment elevation in the anterior leads of a 12-lead electro-cardiogram. She received stent implantation with a 3.5 × 23 mm sirolimus-eluting stent at the proxi-mal portion of left anterior descending artery (LAD) 10 years ago. Dual antiplatelet therapy, however, was discontinued 3 years ago. Urgent coronary angiography demonstrated a near total occlusion at the proximal portion of LAD, which was the same segment of the previous stent implantation (Fig. 1A). Optical coherence tomography (Supplementary Figure 1. A. Angiographic assessment demonstrating severe stenosis in the proximal portion of implanted stent and diffuse haziness in in-stent area; B. Optical coherence tomography (OCT) assessment demonstrating minimal lumen area of 2.17 mm2 with fibrous plaque; C. OCT cross-section demonstrating minimal stent area of 5.71 mm2 in in-stent; D. OCT demonstrating thin-cap neoatheroma (arrowheads in D1 and D2) and plaque rupture (arrow in D2); E. OCT demonstrating thin-cap fibroatheroma (arrowheads in E1, E2, and E3) with intraluminal thrombus (arrow in E1) and ruptured plaque (arrow in E2).INTERVENTIONAL CARDIOLOGYCardiology Journal 2017, Vol. 24, No. 6, 704–705DOI: 10.5603/CJ.2017.0146 Copyright © 2017 Via MedicaISSN 1897–5593704 www.cardiologyjournal.orgIMAGE IN CARDIOVASCULAR MEDICINEVideo 1 — see journal website) demonstrated that a minimal lumen area of 2.17 mm2 in de-novo lesion (Fig. 1B) and minimal stent area of 5.71 mm2 in the in-stent area (Fig. 1C), thin-cap neoath-eroma (Fig. 1, D1), and neoatherosclerotic plaque rupture (Fig. 1, D2) upstream of the culprit site. Furthermore, optical coherence tomography showed thin-cap fibroatheroma with plaque rup-ture of the de novo lesion in the left main bi-furcation area (Fig. 1, E1, E2, E3). Incomplete strut apposition and uncovered struts were not detected. The optical coherence tomography assessment led to another predilatation with a 3.5 × 10 mm noncompliant balloon, and a 3.25 × 38 mm everolimus-eluting stent implan-tation. Postdilatation was achieved with a 3.5 × × 10 mm noncomplicant balloon. Repeated optical coherence tomography assessment demonstrated excellent stent expansion and good strut apposition without edge dissection.Optical coherence tomography provided high-resolution (10 µm) which enabled detection of a thin fibrous cap covering the lipid core (< 65 µm) and allowed characterization of tissue components of atherosclerotic plaques. This case highlights the benefit that optical coherence tomography offers in providing interventional strategies for very late stent thrombosis.Conflict of interest: None declaredwww.cardiologyjournal.org 705Yongcheol Kim et al., OCT assessment of VLST

Very late stent thrombosis derived from thin-cap neoatheroma and fibroatheroma with plaque rupture assessed by optical coherence tomography

https://journals.viamedica.pl/cardiology_journal/article/download/CJ.2017.0146/42644

Very late stent thrombosis derived from thin-cap neoatheroma and fibroatheroma with plaque rupture assessed by optical coherence tomography

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