Usage and quality of water for living were investigated in Tashkent and 3 south-eastern cities in Uzbekistan and 2 north-western cities in Tajikistan, a neighboring country of Uzbekistan. Waterworks were created in urban areas of the region and piped water had high concentration of SO_4^-^2, NO_3^- and Ca^+^2. This indicates that raw water (surface water or groundwater) had been supplied without purification. Groundwater of flatlands in Shahrisabz and Termiz, Uzbekistan showed total hardness of 300-650mg/L and contained many ions when compared with mountain spring water of Ainy, Tajikistan. PO_4^-^3 and NH_4^+ detected in a majority of samples might suggest water resource contamination with fertilizer and excreta
