Periodontal diseases continue to be a major health problem world-wide with the incidence of oral cancer and other disorders are on the rise in developing countries. Oral health also reflects the body health and mental health. For prevention and the treatment of periodontal diseases, Ayurveda may lead to the development of novel preventive, therapeutic and holistic strategies for oral health. This Indian ancient system of medicine not only recommends treatments with specific herbs and minerals to cure various oral diseases but also recommends some daily use therapeutic procedures for the prevention of and maintenance of oral health. Various Ayurvedic herbs and natural products have been used for their pharmacological applications viz. antiulcer, wound healing, anti-inflammatory, antimicrobial and antioxidant properties and have been proven to be safe and effective for oral disease and hygiene including various therapeutic Ayurvedic procedures. Scientific validations of the Ayurveda oral health practices could justify their incorporation into modern oral care. In this paper, an attempt has been made to scientific evidence based therapeutic procedure Dantapavan (tooth brush) of neem (Azadiracta indica) for the prevention and maintenance of oral health and hygiene mentioned in Ayurveda