Introduction: Recently all world is suffering from Pandemic Covid 19. COVID-19 is an infectious disease caused by severe acute respiratory syndrome corona virus 2 (SARS-CoV-2) that is novel corona virus. First case was detected in Wuhan, China. The symptoms are similar as like flu. Most common symptoms are fever, dry cough, breathlessness, sore throat, weakness, bodyaches. These symptoms vary according to individuals. COVID 19 is declared as Pandemic. In Ayurveda, Pandemic is explained in Charaka Samhita Viman Sthana under Janpadodhwansniya Adhyaya. There is no medication for Covid 19. So, we can prevent and defend this disease by boosting own immunity. Ayurveda explained immunity under the heading of Vyadhikshamatwa. In Ayurveda various types of regimens like Dinacharya, Ritucharya, Aharavidhi, Rasayana Chikitsa, Vyayama, Yoga, Pranayama. These all are very much helpful to enhance the immunity. Methods: In this article, information from contemporary texts of Ayurveda in view of Vyadhikshamatva and immunity have been documented to understand treatment approach of Ayurvedic science. Result: The Pandemic like Covid 19 is difficult to manage in current days. But it is possible to prevent and manage by boosting the immunity. Conclusion: This pandemic of Corona virus disease SARS COV2 has no treatment and vaccination available till now. Only prevention is the way by adoption of social distancing as the contaminating rate is very high. So one should understand the importance of healthy life style, good diet habits and daily exercise etc. to acquire immunity. Immunity can be acquired with some herbs and medicines, by following regimen, Proper Rasayana etc. Hence, it is necessary to aware people about health hygine, following healthy regimen, boosting the immunity which is explained in Ayurveda. In the present review article, an attempt has been made to present concept of Vyadhikshamatva specially in current Pandemic COVID 19
