A comparative study on the isolation and cerium (IV) ammonium nitrate mediated oxidative transformation of oleanolic acid and ursolic acid

Abstract

598-603<span style="font-size:11.0pt;mso-bidi-font-size: 10.0pt;font-family:" times="" new="" roman";mso-fareast-font-family:"times="" roman";="" mso-bidi-font-family:"times="" roman";letter-spacing:-.1pt;mso-ansi-language:="" en-gb;mso-fareast-language:en-us;mso-bidi-language:ar-sa"="" lang="EN-GB">Oleanolic acid and Ursolic acid, two important pentacyclic triterpenes have been extracted from two different sources and have been subjected to oxidation using cerium (IV) ammonium nitrate in methanol. Two new oxidation products, namely a lactone and an ester have been obtained which however show decreased antibacterial activity in comparison to the parent compounds.</span