International audienceThe Institut Pluridisciplinaire Hubert Curien (IPHC) is a laboratory with solid foundations and perspectives to overcome future challenges. It is a component of the Centre National de Recherche Scientifique (CNRS) and the university of Strasbourg. It has been founded in 2006 after fusion of three local laboratories in the field of ecology/environment, chemistry and subatomic physics. The activities related with subatomic physics presents a rich history which goes back to the 40’s and is now evolving towards new challenges at the frontier of the innovation with the contribution of other sciences as biology, chemistry, medicine and radiotherapy. The paper will recover a number of past and current activities with emphasis on the link between research and technology