CORE
🇺🇦
make metadata, not war
Services
Services overview
Explore all CORE services
Access to raw data
API
Dataset
FastSync
Content discovery
Recommender
Discovery
OAI identifiers
OAI Resolver
Managing content
Dashboard
Bespoke contracts
Consultancy services
Support us
Support us
Membership
Sponsorship
Community governance
Advisory Board
Board of supporters
Research network
About
About us
Our mission
Team
Blog
FAQs
Contact us
Increasing prevalence of multidrug-resistant non-typhoidal salmonellae, Kenya, 1994–2003
Authors
Anthony C. Hart
Dorothy Kagendo
+7 more
Nyambura Kariuki
Samuel Kariuki
Agnes Munyalo
Lawrence Murungi
Jane Muyodi
Joyce Mwituria
Gunturu Revathi
Publication date
1 August 2005
Publisher
'Elsevier BV'
Doi
Cite
Abstract
Over the last decade there has been a steady increase in the proportion of multidrug resistance among non-typhoidal salmonellae (NTS) isolated from adult patients with bacteraemia in Kenya. The prevalence of NTS multiply resistant to all commonly available drugs including ampicillin, streptomycin, co-trimoxazole, chloramphenicol and tetracycline rose from 31% in 1994 to 42% at present, with concomitantly higher MICs of each drug. Resistance is encoded on large self-transferable 100–110 kb plasmids. Pulsed field gel electrophoresis of XbaI and SpeI digested chromosomal DNA revealed three main digest patterns for Salmonella enterica serotype Typhimurium and two main patterns for Salmonella enterica serotype Enteritidis. Although the genotypes of NTS remained fairly stable over the last decade, the large increase in MICs of all commonly used drugs and increased MICs of ciprofloxacin, poses a major challenge for treatment of invasive NTS infection. © 2004 Elsevier B.V. and the International Society of Chemotherapy. All rights reserved
Similar works
Full text
Available Versions
eCommons@AKU
See this paper in CORE
Go to the repository landing page
Download from data provider
oai:ecommons.aku.edu:eastafric...
Last time updated on 30/10/2022