全例逆流性腎症によると考えられる蛋白尿を術前から有していた.1例ではPaquin法, 2例ではPolitano-Leadbetter法が施行されていた.腎機能の急速な悪化は, 全例で思春期以降で, 2症例では初診時すでにsmall kidneyが認められていたWe report 3 patients progressed to end-stage chronic renal failure after antireflux surgery. Preoperatively, the 3 patients had proteinuria, probably due to reflux nephropathy. Surgical procedures used were Paquin's method in 1 patient and Politano-Leadbetter's method in 2. Rapid deterioration of renal function was observed from puberty in all patients. In addition, renal hypoplasia was suspected in 2 patients. We concluded that both reflux nephropathy and renal hypoplasia played important roles in the progression of renal insufficiency
