Department of Urology, Faculty of Medicine, Kyoto Univeersity
Abstract
1) L-Triiodothyronine (FK-300) was given to 12 patients of male infertility, 3 of azoospermia and 9 of oligospermia. There was an increase in sperm count observed in 8, a rise in sperm motility in 7, and the wife of the highly oligospermic men conceived. 2) The mechanism of action upon the sexual gland of this agent is st i ll unknown, but is considered due to its action upon the spermatogenesis, especially upon the development of the spermatids, and also to its influence on the Thyroidal-Pituitary-Sexual gland system as referred to by Evans and Simpson, etc. 3) No differences of significance w ere noted in its effect between a group of euthyroidism, and a group of hypothyroidism, though this may be due to the scarcity in number of experimental cases
