A case of McCune-Albright syndrome is reported. The patient was a girl aged 8 years. The chief complaints were gait disturbance and a limp. Roentgenograms showed collapse and severe varus deformity of the femoral neck on the right side with 64° of neck-shaft angle. She had an episode of vaginal bleeding at the age 7 years. Valgus osteotomy of the right proximal femur for the correction of coxa vara and a bone transplantation of an allograft from her mother were performed. Seventy degrees of correction were obtained and the discrepancy of limb length was 1cm after the operation. Roentgenograms showed sufficient callus and solid union between the fragments and the grafted bone 1 year after the operation. Frozen allograft bone was very effective in stimulating bone induction even in fibrous lesions of a patient with McCune-Albright syndrome. Immunology of bone grafts, HLA antigens, osteogenesis in grafts, and the etiology of McCune-Albright syndrome were discused
