VANDEPUTTE, LBA

VANDERHEIJDE, DMFM

VANLEEUWEN, MA

VANRIEL, PLCM

VANRIJSWIJK, MH

VANTHOF, MA

The influence of age at onset was studied in a prospective followup of early rheumatoid arthritis (RA). Patients greater-than-or-equal-to 60 years (n = 71) showed significantly more often an onset in both large and small joints and higher disease activity at the start compared with patients &lt;60 years (n = 142). The higher disease activity was still present after 2 years of followup (greater-than-or-equal-to 60 years, n = 46, &lt;60 years, n = 101); as well, there was a tendency towards more radiographic damage. Rheumatoid factor (RF) and DR4 were comparable in both age groups. Our data show a more severe course in older age RA. This disagreement with the literature is probably due to the fact that many studies are cross sectional with unbalance of RF in the 2 age groups.</p

OLDER VERSUS YOUNGER ONSET RHEUMATOID-ARTHRITIS - RESULTS AT ONSET AND AFTER 2 YEARS OF A PROSPECTIVE FOLLOW-UP-STUDY OF EARLY RHEUMATOID-ARTHRITIS

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Proceedings - University of Groningen