Synthetic pesticides are excessively consumed to control crop pests but abundant use of chemicals may implicate the whole ecosystem badly in the end. Despite the growing concern, few natural products are commercialized for pest control whilst on-farm use of existing botanically-based pesticides remains a small, but growing, component of crop protection practice. The experiment was conducted to assess the potential trade-offs of using botanical extracts (Neem leaf extract, NLE, and Moringa leaf extract, MLE) along with synthetic insecticide, Confidor 200 SL, against Aphis gossypii Glover. Meanwhile, impact of these insecticides on natural enemies were also determined in the field experiment. Data were recorded 12h before, as well as 1, 3, and 7 days after the application (DPA) of insecticides. Results revealed that chemical insecticide after 1DPA were showed higher mortality (%) of aphid’s population at leaf (33%) and boll stage (41%), whereas, the botanical treated plots showed lower mortality used alone as well combined application but lower numbers were observed on the negative controls. The same trend of insecticidal activity was observed from all treatments after 3DPA, but interestingly, after 7DPA, the resurgence of beneficial insects were only recorded in botanical extract-treated plots. The Confidor presented an adverse effect on natural enemies whereas no or few natural enemies were observed compared to herbal extracts. Overall, for long-term control, the combined use of botanical insecticides is proved to be more efficient in the management of the aphids than Confidor and caused no or little adverse impact on the beneficial insects
