The objective of this study was to determine whether somatic cell count (SCC) was an effective
test, with a sensitivity exceeding 85%, to determine species-specific bacterial infections.
In addition, the relation between the SCC and various udder pathogen groups was investigated.
SCC thresholds of greater than 200 000 cells/mL were used in quarter and greater than
150 000 cells/mL in composite milk samples. A retrospective study was conducted on a data
set for 89 635 quarter and 345 467 composite cow milk samples. Eleven SCC threshold values
were used to evaluate the diagnostic efficacy for the following bacteria: Gram-positive major
pathogens: Staphylococcus aureus, Streptococcus agalactiae, Streptococcus dysgalactiae and
Streptococcus uberis; Gram-negative major pathogens: Escherichia coli, Klebsiella pneumonia
and Serratia spp.; minor pathogens: coagulase-negative staphylococci, Micrococcus spp.,
Staphylococcus pseudintermedius, Streptococcus pyogenes, Enterococcus faecalis, Enterococcus canis,
Trueperella pyogenes and other Enterobacteriaceae. Sensitivity and specificity were calculated
taking the effect of clustering into account with quarter milk samples. Most samples yielding
major Gram-positive pathogens (88.9% in quarter and 79.9% in composite samples) and minor
pathogens (61.4% in quarter and 51.7% in composite samples) had SCC greater than
200 000 cells/mL. Sensitivity of the SCC test to detect major pathogens at an SCC threshold of
greater than 200 000 cells/mL in quarter samples and greater than 150 000 cells/mL in
composite milk samples was 88.2% and 84.2%, respectively, but specificity was low (57.7% and
52.8%, respectively).http://www.jsava.co.zaam2017Animal and Wildlife SciencesProduction Animal Studie