Background and Purpose: Post-cesarean pain is the most common post-operative complaint and has been shown with little evidence that gabapentin reduces acute pain after cesarean section. The aim of this study was to evaluate the effect of Gabapentin on pain reduction after cesarean section.
Methodology: This is a double blind randomized clinical trial. Women referring to the center for treatment, educational and research of martyrs who are planning to perform elective cesarean section with spinal anesthesia are included in the study. After obtaining satisfaction from patients and controlling entry and exit criteria, they are selected as research units. The goals and methods of work are described to patients. Patients are divided into two randomized groups that consist of the control group (one capsule of the placebo) and the intervention group (one capsule of gabapentin 300 mg). Both groups receive oral medication after cesarean section. After cesarean section, the pain intensity of the patients was recovered at hours 2, 4, 6, 12 and 24 after cesarean section based on VAS (Visual Analog Scale). Statistical analysis was performed using SPSS20 software and chi-square test with a significance level of p <.0.005.
Results: I n the intervention group, more pain was observed during the first 24 hours than the control group (p = 0.043). Also, the differences in the level of satisfaction with pain-relieving drugs were different in two groups (p = 0.000). Patients in the two groups did not differ significantly in terms of lactation, frequency of drug use, visual acuity of pain, side effects such as itching, blurred vision, abnormal eye movement, and duration of the first dose of opiate.
Conclusion: This study has shown that gabapentin has been used to relieve the patient's pain.
Key words: Gabapentin, Pain, Caesarean sectio
