Background and Aim: Polycystic ovary syndrome (PCOS) is a common disorder in women
of childbearing age that can be associated with adverse pregnancy complications. The aim of
this study was to compare the adverse pregnancy consequences between pregnant women
with PCOS and control group in Qazvin.
Materials and Methods: In this study, 150 pregnant women with PCOS aged 18-35 years
with gestational age of more than 20 weeks were selected as our case group based on
Rotterdam criteria and our control group included 150 pregnant women without PCOS. The
groups were compared in terms of pregnancy complications including gestational diabetes,
preeclampsia, preterm delivery, low birth weight, and neonatal admission to the neonatal
intensive care unit (NICU).
Results: There were no significant differences between the two groups in terms of
demographic data including age, weight, height and BMI. In the case group (PCOS) we found
gestational diabetes in 33 cases (64.7%) (P=0.021), preeclampsia in 44 cases (67.7%)
(P=0.002), and preterm delivery 70 in cases (75.3%) which indicated a significant difference
between the case and control groups (P<0.0001). The case group had higher neonatal
complications than control group in regard to low birth weight (40 cases, 64.5%, P=0.008)
and NICU admission (30 cases, 66.7%, P=0.015).
Conclusion: The results of this study showed that PCOS, due to its metabolic effects, may
increase the incidence of gestational diabetes, preeclampsia, preterm delivery, low birth
weight or macrosomia and long term NICU admission.
Keywords: Polycystic ovary syndrome, Premature birth, Gestational diabetes, Pre-eclampsi
