The American Society for Gastrointestinal Endoscopy\u27s GIE Editorial Board reviewed original endoscopy-related articles published during 2019 in Gastrointestinal Endoscopy and 10 other leading medical and gastroenterology journals. Votes from each individual member were tallied to identify a consensus list of 10 topic areas of major advances in GI endoscopy. Individual board members summarized important findings published in these 10 areas of disinfection, artificial intelligence, bariatric endoscopy, adenoma detection, polypectomy, novel imaging, Barrett\u27s esophagus, third space endoscopy, interventional EUS, and training. This document summarizes these “top 10” endoscopic advances of 2019