National Society of Pediatric Surgery of the Republic of Moldova
Abstract
Introduction. Adhesive intestinal obstruction (AIO) is one of the most difficult and unsolved problems of
the abdominal surgery in children.
Aim of the study. To explore the possibility of using hyaluronic acid solution for the treatment of
intraperitoneally adhesions in children.
Methods. 84 children were operated on AIO. The children were divided into two groups. HAS was not used
in I group (56 patients). HAS was used in II group (28 patients). The follow-up of children from 1 to 4 years.
From 84 patients on AIO: 21 (25 %) operated on for early adhesive intestinal obstruction, 63 (75 %) – on late
adhesive intestinal obstruction. Recurrent AIO was in 12 (14,29 %) children.
Results. In the I group (56 children) in the first year after surgery with adhesion syndrome turned 13 (23,21
%) children, up to 4 years - 20 (35,71 %) patients. In the II group (28 children) adhesion syndrome (cured
conservatively) over 3 years postoperative period turned 2 (7,14 %) patients, indicating the effectiveness of
hyaluronic acid solution for the purpose for treatment of the adhesions abdominal cavity in children.
Conclusion. The hyaluronic acid solution is effective in the treatment of adhesive intestinal obstruction in
children and is accompanied by a recurrence of the adhesion syndrome 7,14 % (n=28 children) on the difference
in the group without using it – 35,71 % (n=56 children)
