Impact assessment of polymorphic markers of the genes that determine the B, E apolipoproteins metabolism and lipid disturbances in patients with CAD

Abstract

Laboratorul de Genetică, Universitatea Stat Medicină şi Farmacie ”N.Testemiţanu”The impact of polymorphic markers of the genes that determine the B, E apolipoproteins metabolism and lipid disturbances in patients with CAD was studied. Lipid profiles changes in patients with CAD may be influenced by genotypic and allelic frequencies difference of ApoB and ApoE gene. A fost studiat impactul markerilor polimorfi ai genelor ce determină metabolismul apolipoproteinelor B, E şi perturbările lipidice la pacienţii cu CPI. Dereglările profilului lipidic la pacienții cu CPI s-ar putea atribui parţial prin diferenţa frecvenţelor genotipice şi alelice ale genelor APOB și APOE

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