Sedaia, Ecaterina

Institutional Repository in Medical Sciences of Nicolae Testemitanu State University of Medicine and Pharmacy of the Republic of Moldova

73  ROLUL ULTRASONOGRAFIEI ÎN EVALUAREA PACIENŢILOR CU SINDROM METABOLIC  Ecaterina Sedaia (Conducător ştiinţific: Valeriu Revenco, dr. hab. şt. med., prof. univ., Disciplina cardiologie, Departamentul de medicină internă)  Introducere. Sindromul metabolic (SM) şi, în special, obezitatea viscerală, actualmente reprezintă una dintre cele mai importante probleme medicale pe plan global, necesitând o abordare complexă pentru prevenirea şi micşorarea cât mai precoce a riscului cardiometabolic. Scopul lucrării. Aducerea la cunoştinţă despre metodele ultrasonografice (USG) cele mai utilizate şi răspândite de apreciere şi cuantificare a ţesutului adipos (ŢAd) şi a riscului cardiometabolic la pacienţii cu SM.  Material şi metode. Analiza datelor bibliografice recente ce vizează importanţa clinică de utilizare a USG în evaluarea ŢAd la pacienţii cu SM pentru stratificarea riscului cardiometabolic. Rezultate. Rolul definitiv al ŢAd şi, anume, a celui visceral, în patofiziologia SM şi a obezităţii este cunoscut şi acceptat de societatea medicală. USG este un test medical noninvaziv, relativ necostisitor pentru evaluarea ŢAd în practica medicală cotidiană. Au fost elaboraţi unii parametri şi indici specifici de apreciere şi cuantificarea ŢAd (fie visceral, fie subcutanat) cu USG pentru determinarea suplimentară a riscului cardiometabolic şi prognosticului unui pacient cu SM şi/sau obezitate. Unii din aceşti parametri (grosimea ŢAd intra-abdominal, ŢAd epicardic, grosimea ŢAd peri- şi pararenal, grosimea ŢAd subcutanat), au corelaţie bună cu tomografia computerizată (TC) şi rezonanţa magnetică (RMN), alţii, la moment, fiind insuficient evaluaţi (indicele abdominal de ŢAd, grosimea ŢAd pre-peritoneal, grosimea ŢAd mesenteric). Concluzii. Unii parametri şi indici obţinuţi prin evaluarea USG a ŢAd au corelaţie foarte bună cu TC/RMN şi pot fi pe larg utilizaţi la pacienţii cu SM şi/sau obezitate pentru determinarea riscului cardiometabolic.  Cuvinte cheie: sindrom metabolic, ultrasonografie, ţesut adipos.   THE ROLE OF ULTRASONOGRAPHY IN EVALUATION OF PATIENTS WITH METABOLIC SYNDROME  Ecaterina Sedaia (Scientific adviser: Valeriu Revenco, PhD, univ. prof., Discipline of cardiology, Department of internal medicine)  Introduction. Metabolic syndrome (MetS) and, especially, visceral obesity, represents one of the most important and global medical problems now, which needs complex approach for prevention and early reduction of cardiometabolic risk. Objective of the study. The aim is to provide the information about the most used and shared ultrasonographic (USG) techniques for determination and quantification of adipose tissue (AT) and cardiometabolic risk in patients with MetS. Material and methods. To analyze recent data about clinical importance and usefulness of USG in evaluation of AT in patients with MetS for cardiometabolic risk stratification. Results. The definitive role of AT and, especially, of visceral one, in pathophysiology of MetS and obesity is known and accepted by medical community. USG is a noninvasive medical technique, relatively inexpensive for determination of AT in everyday practice. Several specific parameters and indices for determination and quantification of AT (visceral and subcutaneous) by USG were elaborated for additional appreciation of cardiometabolic risk and prognosis of patients with MetS and/or obesity. Some of these parameters and indices (intra-abdominal fat thickness (FT), epicardial FT, peri- and para-renal FT) are well correlated with computer tomography (CT) and magnetic resonance (MRI), others are insufficiently studied at present (abdominal wall FT, pre-peritoneal FT, mesenteric FT). Conclusions. Several parameters and indices of evaluation of AT that are obtained by USG have good correlation with CT/MRI and could be largely used for the evaluation of patients with MetS and/or obesity for cardiometabolic risk stratification. Keywords: metabolic syndrome, ultrasonography, adipose tissue.  

THE ROLE OF ULTRASONOGRAPHY IN EVALUATION OF PATIENTS WITH METABOLIC SYNDROME

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THE ROLE OF ULTRASONOGRAPHY IN EVALUATION OF PATIENTS WITH METABOLIC SYNDROME

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Institutional Repository in Medical Sciences of Nicolae Testemitanu State University of Medicine and Pharmacy of the Republic of Moldova