Objective: To assess the effects of serum and follicularfluid total oxidant (TOC) levels, total antioxidant capacity (TAC), and oxidative stress index (OSI) on oocytematuration, fertilization, embryogenesis, and clinicalpregnancy outcomes in In Vitro Fertilization (IVF) cyclesof infertile patients.Material and Methods: One hundred patients having infertility and underwent ART enrolled the study group andblood samples were collected on gonadotropin starting,oocyte pick-up (OPU) and embryo transfer (ET) days.Additionally, follicular fluid specimen obtained duringOPU was collected. TOC, TAC levels and OSI in serumsamples and follicular fluid specimens between clinicallypregnant and non-pregnant patients were compared.Results: No significant difference was noted between clinically pregnant and nonpregnant patients in terms of thewoman’s age, duration of infertility, ovarian reserve ornumber of transferred embryos. There was also no significant difference in TAC, TOC and OSI levels in serumsamples obtained during three phases of treatment cycle(basal gonadotropin starting day, OPU day and ET day)and in follicular fluid samples.Conclusion: TAC, TOC and OSI seem to be ineffective topredict clinical pregnancy as an outcome in patients whounderwent ART.Keywords: infertility, iotal oxidant capacity, total antioxidant capacity, oxidative stress index</p
