Even though fiber-optic communication systems have been engineered to nearly approach the Shannon capacity limit, they still cannot meet the exponentially-growing bandwidth demand of the Internet. Space-division multiplexing (SDM) has attracted considerable attention in recent years due to its potential to address this capacity crunch. In SDM, the transmission channels support more than one spatial mode, each of which can provide the same capacity as a single-mode fiber. To make SDM practical, crosstalk among modes must be effectively managed. This dissertation presents three techniques for crosstalk management for SDM. In some cases such as intra-datacenter interconnects, even though mode crosstalk cannot be completely avoided, crosstalk among mode groups can be suppressed in properly-designed few-mode fibers to support mode group-multiplexed transmission. However, in most cases, mode coupling is unavoidable. In free-space optical (FSO) communication, mode coupling due to turbulence manifests as wavefront distortions. Since there is almost no modal dispersion in FSO, we demonstrate the use of few-mode pre-amplified receivers to mitigate the effect of turbulence without using adaptive optics. In fiber-optic communication, multi-mode fibers or long-haul few-mode fibers not only suffer from mode crosstalk but also large modal dispersion, which can only be compensated electronically using multiple-input-multiple-output (MIMO) digital signal processing (DSP). In this case, we take the counterintuitive approach of introducing strong mode coupling to reduce modal group delay and DSP complexity
