Breast milk is the most important food, especially in the first months of a baby's life. The best nutrition on the first day of a baby's life is colostrum. Delayed and insufficient milk production can cause mothers not to give breast milk to their babies. The process of releasing milk also depends on the Let-Down Reflex (LDR). One way to facilitate breast milk production is to apply the Stimulation of Endorphin Massage, Oxytocin Massage, and Suggestive (SPEOS) method. The purpose of this study was to determine the effect of the SPEOS Method on the Let-Down Reflex (LDR) Activation in Postpartum. The study design used a pre-experimental one-group pre-test - post-test. The location of the study was conducted at the public health of Denpasar which provides delivery services. The research period was from May to October 2019. The population was the postpartum mother who was treated at the public health care of Denpasar and fulfilled the specified inclusion criteria. The data collection instrument used a questionnaire. Statistical analysis with Wilcoxon test. The result found the median of LDR postpartum before the SPEOS method (2 with a range of 1-3) and after the SPEOS method (5 with a range of 4-6) indicated an increase in the LDR score (p-value <0,001). The conclusion is that the SPEOS method increases the activation of Let Down Reflexes (LDR) in postpartum. Recommendation to public health centers and health workers to compile and set operational standards for SPEOS procedures and implement this method for each postpartum mother
