Over the last two decades, the terms leadership and leadership styles has become more important and widely used in the world. This research examined the enhancement of leadership styles on sustainability of the entrepreneurial practices in higher institution with reference to Covenant University Ota. Three hundred and two (302) members of covenant University Alumni (2007-2018) were randomly sampled by correspondence via emails through the alumni office. The study employed descriptive and inferential statistics. Regression analysis was used to test the hypothesis to determine the weight of the independent variables on the dependent variables. The result of analysis shows that Autocratic and Transformational style has significant effect on the practice of entrepreneurship and if properly applied would increase the number of entrepreneurs in the country, reduce unemployment as well lead to positive economic growth of the Nation Nigeria
