Plasma hs-crp level as a predictor of left ventricular function & myocardial reperfusion injury in patients with acute myocardial infarction-thrombolysed
1. In the estimation of High sensitive- C –reactive protein, the high risk group predominated at 52% with a mean of 6.72±1.76, intermediate risk - 25% with a mean of 2.02±0.083 and low risk - 23% with a mean of 0.75±0.239.
2. In all the groups male patients predominated.
3. In the low and intermediate group the window period was predominantly in the range of 3- 6 hrs, in high risk group it was > 6 hrs.
4. The mean ejection fraction in the low risk was 57±11, intermediate risk was 54.12±10.76 and in high risk group it was 50±10.8.
5. The reperfusion injury was only 4% in the low risk group, 8% in the intermediate risk and it was higher in the high risk group at 42%.
6. The most common site of acute myocardial infarction was extensive anterior wall myocardial infarction followed by inferior wall myocardial infarction.
7. Among women, 55.55% of post menopausal women had acute
myocardial infarction.
8) Oral contraceptive pill was a risk factor in 1 patient (5.5%).
9. Smoking was one of the major risk factor in 79.2% of male patients.
10. Obesity was found to be a risk factor in 22% of patients.55.55% among female were obese.
11. Diabetes was found in 29% of patients of which 79.3% were male.
12. Hypertension was seen in 49% patients. Of these 79.59% were male.
CONCLUSION :
In this Present study it is found that Ejection Fraction is lower in the high CRP group. Reperfusion injury is lower in the low and intermediate risk group according to the High Sensitive C –Reactive Protein assay. As echocardiogram was done only on day three after Acute myocardial infarction, a lot of stunned myocardium may be present, which is the limitation of this study
