We present the analysis of advection-diffusion equations with random coefficients on moving hypersurfaces. We define weak and strong material derivative, that take into account also the spacial movement. Then we define the solution space for these kind of equations, which is the Bochner-type space of random functions defined on moving domain. Under suitable regularity assumptions we prove the existence and uniqueness of solutions of the concerned equation, and also we give some regularity results about the solution