The purpose of this study was to develop a structural equation model to examine the effect of organizational resilience, on perceived job security and employee engagement, among Thai hotel employees during the Covid-19 pandemic. A quantitative approach was applied using an online questionnaire. A purposive sampling technique was employed to collect data, based on the respondents’ specific levels of employee tenure and work experience during the pandemic. A total of 485 Thai hotel employees participated in the study. Data were analyzed through PLS-SEM. The results of the analysis revealed a good fit of the model with the empirical data (CMIN/DF = 2.82, RMSEA = 0.06, CFI = 0.97, TLI = 0.96). Moreover, the findings indicated that organizational resilience had positive direct and indirect effects on employee engagement during the unprecedented outbreak of Covid-19. A theoretical foundation was established to explore possible key drivers of employee engagement amid a globally disruptive event. Hotel businesses can employ this model for better preparedness in forthcoming fast-changing situations