Background: Diabetes Mellitus is a metabolic disease that cause its patient need a long life maintenance.
Diabetes Mellitus management in daily life is a complex activity and need an understanding about medicines, healthy diet, physical activities, and glycemic control. All those things is a personal responsibility of patient with Diabetes Mellitus Type 2. The objective of this systematic review was to describe the self-care adherence experience in patient with Diabetes Mellitus Type 2. Method: 15 best articles were found using PECOT framework in some databases; EBSCO, Science Direct, Scopus, and
Journal of Universitas Airlangga. Those articles have been chosen based on some criteria. Result: Self-care
therapeutic regiment for patient with Diabetes Mellitus Type 2 are physical activities, diet, self-monitoring
blood glucose (SMBG), and glycemic control. But most of respondents were disobey the therapy caused by various factors. Depression is one of the reason. Conclusion: Nursing intervention was needed to increase self-care adherence in patient with Diabetes Mellitus Type 2
