Photoplethysmography (PPG) is an optical measurement method for blood pulse wave monitoring. The method has been widely applied in both clinical and wearable devices to collect physiological parameters, such as heart rate (HR) and heart rate variability (HRV). Unfortunately, the PPG signals are very vulnerable to motion artifacts, caused by inevitable movements of human users. To obtain reliable results from PPG-based monitoring, methods to denoise the PPG signals are necessary.
Methods proposed in the literature, including signal decomposition, time-series analysis, and deep-learning based methods, reduce the effect of noise in PPG signals. However, their performance is insufficient for low signal-to-noise ratio PPG signals, or limited to noise from certain types of activities. Therefore, the aim of this study is to develop a method to remove the motion artifacts and reconstruct noisy PPG signals without any prior knowledge about the noise.
In this thesis, a deep convolutional generative adversarial network (DC-GAN) based method is proposed to reconstruct the PPG signals corrupted by real-world motion artifacts. The proposed method leverages the temporal information from the distorted signal and its preceding data points to obtain the clean PPG signal. A GAN-based model is trained to generate succeeding clean PPG signals by previous data points. A sliding window moving at a fixed step on the noisy signal is used to select and update the input for the trained model by the information within the noisy signal. A PPG dataset collected by smartwatches in a health monitoring study is used to train, validate, and test the method in this study. A noisy dataset generated with real-world motion artifacts of different noise levels and lengths is used to evaluate the proposed and baseline methods. Three state-of-the-art PPG reconstruction methods are compared with our method. Two metrics, including maximum peak-to-peak error and RMSSD error, are extracted from the original and reconstructed signals to estimate the reconstruction error for HR and HRV.
Our method outperforms state-of-the-art methods with the lowest values of the two evaluation matrices at all noise levels and lengths. The proposed method achieves 0.689, 1.352 and 1.821 seconds of maximum peak-to-peak errors for 5-second, 10-second, and 15-second noise at the highest noise level, respectively, and achieves 0.021, 0.048 and 0.067 seconds of RMSSD errors for the same noise cases.
Consequently, our method performs the best in reconstructing distorted PPG signals and provides reliable estimation for both HR and HRV
