New generation of steroidal 4-aminoquinolines as potent antimalarials

Abstract

Sintetisani su novi steroidni 4-amino-7hlorohinolinski derivati i isptana je njihova in vitro antimalarijska aktivnost prema CQ rezistentnim i CQ osetljivim sojevima P. falciparum.Here we present synthesis of new steroidal 4-amino-7-chloroquinolines and dscuss their in vitro antimalarial activities against CQ-resistant and CQ-susceptible P. falciparum stains