The objective of this study was to determine the most adequate process parameters, using a green extraction method, which ensures maximal utilization of Sambucus nigra L. fruit. Ultrasound-assisted extraction was applied for the isolation of phenolic compounds from elderberries and for obtaining extracts rich in anthocyanins. The UAE experiment was performed at sonication amplitude in the range from 20 to 100%. The highest extraction yield (47.28%) was achieved at 100% amplitude, while the lowest yield (27.70%) was achieved at 20% amplitude. The UAE extract of elderberry obtained at amplitude of 100% proved to be the best in terms of the content of total phenols and monomeric anthocyanins. According to the obtained results, it can be concluded that the suggested extraction approach has a potential for the production of new pharmacologically-active fractions
