Fibronectin isoforms in the blood of patients with chronic diffuse liver disease

Abstract

Chronic diffuse liver disease is characterized by the steady progression of fibrosis with the accumulation of excessive extracellular matrix and scar tissue in the parenchyma of the organ. Fibronectin plays a vital role in tissue repair. Glycoprotein isoforms are simultaneously part of the fibrous matrix of the liver and circulate in plasma. The expression and content of plasma and cellular fibronectin depends on the phase of the disease and the stage of progressive fibrosis.The aim of the study was to determine the level of plasma and cellular forms of fibronectin in chronic diffuse liver disease

    Similar works