Objective: Fatigue is one of the tormentest symptom of the Multiple Sclerosis that decrease
self care ability and role performance of patients and potential of activity of daily living. The
purpose of this study was to assess the effect of Orem self-care program on fatigue and
activity of daily living (ADL) in Multiple Sclerosis clients. Materials & Methods: This quasi
experimental study was a clinical trial research that was done on seventy multiple sclerosis
patients whom were selected randomly from MS association and assigned to
