Is Deep Brain Stimulation a Desirable Therapy for Parkinson’s Disease?

Abstract

Parkinson’s disease is a neurodegenerative disorder that currently impacts 6.1 million people globally. Although it has different presentations, its core features are tremors, postural instability, bradykinesia (slowing of movement), and psychological disabilities such as mood disorders and cognitive decline. A primary treatment is Levodopa, but it has limited success. A promising treatment called Deep Brain Stimulation (DBS) has been shown to induce significant improvements in motor skills where Levodopa has failed to help. Deep Brain Stimulation works via implanted electrodes. It has been used successfully in many studies to decrease motor issues associated with Parkinson’s, but potential side effects pose a problem. Overall though, DBS is a promising field of study in the ongoing attempt to find treatments for Parkinson’s disease, especially as we identify specific aspects of DBS that improve the risk to benefit ratio. This review of the current literature was conducted in order to determine the efficacy and safety of DBS as a treatment for PD

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