Water is one of the natural resources which is essential to sustain life. Water pollution is any chemicals, physical or biological that changes the quality of water and has harmful effects on any living organism that uses it. When humans drink polluted water, it often has serious affects on their health. The objective of the study is 1) to evaluate the nature of the ground water in study area, 2) to study the Socio-economic characteristics of the respondents, 3) to examine the awareness of the respondents about the water pollution, and to find out the methods to control the ill effects of water pollution on human health. The present study was conducted to assess the ill effects of water pollution on human health in Erumapalayam village in Salem District. Salem is the fifth largest city in Tamil Nadu State. A sample of 50 respondents was selected through simple random sampling techniques. The data was collected through well structured interviewing schedule. The collected data was analyzed by using descriptive and inferential statistics. The physical and chemical analysis conducted the water sample, it is found that the appearance of samples is slight-brownish color and they have objectionable odour and taste, Turbidity of the samples is found to be not in the range of permissible limit, I.e., 36 mg/L. As per the standard of Central Public Health Engineering Environmental Organization (CPHEEO) water sample is physically and chemically not potable due to appearance of odour and TDS, ALK, TH, FE, NO3 and C1 value exceeds the maximum permissible limits