It is undeniable that the Covid-19 pandemic has significantly impacted the lives of the majority of Americans. The effects of the Covid-19 virus, however, are not equally distributed among the U.S. population. In particular, Black Americans and Republican Americans experienced disproportionate Covid-19 cases and deaths. This thesis explores the reasons why these two populations experienced unequal Covid-19 outcomes and determines where to place responsibility in each case. Using empirical evidence, I will first investigate the nature of the causes behind these disparities. Then I will highlight the similarities between the causes of unequal Covid-19 outcomes for Black Americans and for Republican Americans. Finally, I will use these comparisons to assess where responsibility should be placed in both cases. This evaluation sheds light on important philosophical principles and suggests policy responses based on responsibility