Today, the diffusion of neoplastic diseases is a widespread phenomenon. Thus, it is always
necessary to identify new molecules able to fight them. In this paper, we will deal with the interesting
antineoplastic properties of green tea. We will describe the different and plausible anticancer
mechanisms of epigallocatechin gallate (EGCG), the major polyphenol found in green tea, and in
particular the biochemical and computational discovery of a new target for the treatment of this
disease will be discussed. The bio-active substances present in tea are essentially represented by
methylxanthines, as well as by the antioxidant phenolic fraction (flavonoids). Among the other active
substances contained in lower concentrations there are vitamins (B, C and K), amino acids (L-theanine)
and minerals (aluminium and manganese). Tea extracts, particularly EGCG, could represent the starting
point for the potential emergence of new drugs for the treatment of neoplastic diseases. Other
activities of tea, as the involvement in neurodegenerative diseases prevention, as well as the
antioxidant, antibacterial, antifungal and antiviral effects, will be also briefly described
