Preparation of hybrid nanoparticles based on interaction of block polyelectrolytes with atypical ions

Abstract

The Thesis deals with the co-assembly behaviour of cationic diblock copolymers poly(2- vinyl pyridine)-b-poly(ethylene oxide), P2VP-b-PEO, and poly(ethylene oxide)-b-poly(2- (N, N, N′, N′-tetramethyl guanidinium) ethyl acrylate), PEO-b-PGEA, with closo- dodecaborate anion, [B12H12]2- , in aqueous solutions. Formation of stable PEO-b- PGEA/[B12H12] nanoparticles was investigated by static and dynamic light scattering and 1 H NMR spectroscopy, and they were visualized as spherical nanoparticles by cryo- TEM imaging. According to the NMR results, both studied diblock copolymers form core- corona micelles with dodecaborate. The micellar molar mass and the aggregation number of PEO-b-PGEA/[B12H12] micelles were obtained in water and 0.156 M NaCl solution by standard Zimm method. For this, refractive index increment was evaluated by refractometer. The studied nanoparticles are promising for the boron delivery in medicine